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Storage stability of non-encapsulated pneumococci in saliva is dependent on null-capsule clade, with strains carrying <i>aliC</i> and <i>aliD</i> showing a competitive disadvantage during culture enrichment

2025-04-13

Abstract excerpt

<h4>Background</h4> Non-encapsulated Streptococcus pneumoniae (NESp) represent up to 19% of circulating pneumococci and exhibit high rates of antimicrobial resistance. Saliva is increasingly used as a pneumococcal carriage study specimen, and we recently developed a qPCR assay to enhance carriage surveillance and characterization of NESpn in saliva. Previous work has established that pneumococci remain viable in...

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Literature Corpus work
28a4a6e4-53cc-56cb-aeea-558fdf396d0f
DOI
10.1101/2025.04.12.648276
Open publication

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Storage stability of non-encapsulated pneumococci in saliva is dependent on null-capsule clade, with strains carrying <i>aliC</i> and <i>aliD</i> showing a competitive disadvantage during culture enrichmentDOI 10.1101/2025.04.12.648276
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