Article

Genetic, transcriptome, proteomic and epidemiological evidence for blood brain barrier disruption and polymicrobial brain invasion as determinant factors in Alzheimer’s disease

2016-10-12

Abstract excerpt

Multiple pathogens have been detected in Alzheimer’s disease (AD) brains. A bioinformatics approach was used to assess relationships between pathogens and AD genes (GWAS), the AD hippocampal transcriptome and plaque or tangle proteins. Host/pathogen interactomes ( C.albicans , C.Neoformans , Bornavirus, B.Burgdorferri , cytomegalovirus, Ebola virus, HSV-1, HERV-W, HIV-1, Epstein-Barr, hepatitis C, influenza, C...

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Literature Corpus work: 27a23716-0f02-5a28-b978-ae12004abb9a
DOI: 10.1101/080333

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