Article

Placental extracellular vesicles from early-onset but not late-onset preeclampsia induce a pro-vasoconstrictive and anti-vasodilatory state in resistance arteries

2024-06-06

Abstract excerpt

<h4>Background</h4> The human placenta releases large numbers of extracellular vesicles (EVs) into the maternal circulation throughout pregnancy. In preeclampsia, a hypertensive disorder of pregnancy, the number of EVs increases and the cargo they carry is altered. We investigated whether human placental EVs from pregnancies complicated by preeclampsia directly alter maternal vascular function, a hallmark of the...

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Literature Corpus work: 27929c78-b295-5bb9-8aa6-7932345e47e9
DOI: 10.1101/2024.06.04.597453

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