Systemic responses to oral hyaluronic acid: A clinical randomized placebo-controlled study of plasma immune and metabolomic responses

Abstract excerpt

<title>Abstract</title> <p>Oral hyaluronan (HA) supplementation has shown clinical benefits, but its systemic effects remain insufficiently characterized. We focused on the systemic effects of oral HA (1.8 MDa) at 60 mg/day (SH60), 120 mg/day (SH120), or placebo for 12 weeks in 150 healthy donors. Within this randomized, double-blind, placebo-controlled study, plasma samples were analyzed to assess changes in imm...

Topics

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• Acne and Rosacea Treatments and Effects
• Aging
• Bayes Theorem
• Cancer, Lipids, and Metabolism
• Fatty Acids
• Genome-Wide Association Study
• Mendelian Randomization Analysis
• Nutritional Studies and Diet

Identifiers and source

Literature Corpus work

27594e34-642c-5b7d-9385-15caebe58f12

DOI

10.21203/rs.3.rs-10165587/v1