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Article

Epigenetic regulation of miR-218 and its host gene, SLIT2 in breast cancer

2016-03-31

Abstract excerpt

Numerous studies have shown that microRNAs are deregulated in various types of cancer. Although miR-218 aberrant expression has been documented in various cancers, the epigenetic regulation of miR-218 is unclear in breast cancer. Our results demonstrate that treatment of breast cancer cells with demethylating agent, 5-azacytidine, resulted in increased expression of miR-218 and its host gene slit-2, suggesting tha...

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Identifiers and source

Literature Corpus work
27205db5-4033-5f99-86ea-1777bfaa2107
DOI
10.1101/046482
Open publication

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