Article

Methylation at nucleotide C <sup>62</sup> in spliceosomal RNA U6 alters mRNA splicing which is important for embryonic development

2019-06-05

Abstract excerpt

Understanding the regulation of development can help elucidate the pathogenesis behind many developmental defects found in humans and other vertebrates. Evidence has shown that alternative splicing of messenger RNA (mRNA) plays a role in developmental regulation, but our knowledge of the underlying mechanisms that regulate alternative splicing are inadequate. Notably, a subset of small noncoding RNAs known as scaR...

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Literature Corpus work: 267cdac0-c141-5c21-9e39-f42e9648c811
DOI: 10.1101/661876

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