Notebook-based alignment of human and agentic reasoning in single-cell biology

Abstract excerpt

Agentic AI is increasingly deployed on complex problems, often using chain-of-thought prompting to ground predictions in stepwise reasoning. In biomedical research, assistive agents could make this reasoning accessible to human scientists: for example, intermediate conclusions could be critically evaluated based on shared reasoning and sycophancy – the tendency to affirm a user’s claims regardless of their validit...

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• Diagnosis, Differential
• Phenotype
• Rare Diseases

Identifiers and source

Literature Corpus work

25a3471c-9c00-5346-a957-fc26d37cb91a

DOI

10.1101/2025.11.24.689256