Article

Targeting the intestinal circadian clock by meal timing ameliorates gastrointestinal inflammation

2023-01-25

Abstract excerpt

<h4>Objective</h4> Impaired clock genes expression has been observed in biopsy samples from patients with inflammatory bowel disease (IBD). Disruption of circadian rhythms, which occurs in shift workers, has been linked to an increased risk of gastrointestinal diseases, including IBD. The intestinal clock balances gastrointestinal homeostasis by regulating the microbiome. Here we characterize intestinal immune fu...

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Literature Corpus work: 258f0b11-3c5e-5ea3-a3b4-60474f377172
DOI: 10.1101/2023.01.24.525433

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