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Long non-coding RNA MIR4435-2HG: a key molecule in progression of cancer and non-cancerous disorders

17 Jun 2022

Abstract excerpt

MIR4435-2HG (LINC00978) is a long non-coding RNA (lncRNA) that acts as an oncogene in almost all cancers. This lncRNA participates in the molecular cascades involved in other disorders such as coronary artery diseases, osteonecrosis, osteoarthritis, osteoporosis, and periodontitis. MIR4435-2HG exerts its functions via the spectrum of different mechanisms, including inhibition of apoptosis, sponging microRNAs...

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PMID: 35715800
DOI: 10.1186/s12935-022-02633-8

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