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Nanocurcumin alleviate inflammation and oxidative stress in LPS-induced mastitis model via activation of Nrf2 and suppressing TLR4 mediated NF-κB and HMGB1 signaling pathways

2021-05-11

Abstract excerpt

Mastitis is a worldwide serious disease of the mammary gland. Curcumin is a pleiotropic polyphenol obtained from turmeric, but it is hydrophobic and rapidly eliminated from the body. However, nanoformulation of curcumin significantly improves its pharmacological activity by enhancing its hydrophobicity and oral bioavailability. Our study aimed to investigate the possible anti-oxidant and anti-inflammatory effects...

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Literature Corpus work
24e58e21-3e06-57aa-a75d-b9abfbb3c1be
DOI
10.21203/rs.3.rs-447345/v1
Open publication

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