Article

Resurrection of plant disease resistance proteins via helper NLR bioengineering

2022-12-11

Abstract excerpt

Parasites counteract host immunity by suppressing helper NLR proteins that function as central nodes in immune receptor networks. Understanding the mechanisms of immunosuppression can lead to strategies for bioengineering disease resistance. Here, we show that a cyst nematode virulence effector binds and inhibits oligomerization of the helper NLR protein NRC2 by physically preventing intramolecular rearrangements...

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Literature Corpus work: 24e18310-eecb-5da7-ac1b-c09c4bd3577a
DOI: 10.1101/2022.12.11.519957

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