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The nucleotide‐binding domain of NRC ‐dependent disease resistance proteins is sufficient to activate downstream helper NLR oligomerization and immune signaling

17 May 2024

Abstract excerpt

Nucleotide-binding domain and leucine-rich repeat (NLR) proteins with pathogen sensor activities have evolved to initiate immune signaling by activating helper NLRs. However, the mechanisms underpinning helper NLR activation by sensor NLRs remain poorly understood. Although coiled coil (CC) type sensor NLRs such as the Potato virus X disease resistance protein Rx have been shown to activate the oligomerization of...

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PMID: 38757730
DOI: 10.1111/nph.19818

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