Back to search

Article

Identifying potential drug targets and candidate drugs for COVID-19: biological networks and structural modeling approaches

2021-05-17

Abstract excerpt

<h4>Background: </h4> Coronavirus (CoV) is an emerging human pathogen causing severe acute respiratory syndrome (SARS) around the world. Earlier identification of biomarkers for SARS can facilitate detection and reduce the mortality rate of the disease. Thus, by integrated network analysis and structural modeling approach, we aimed to explore the potential drug targets and the candidate drugs for coronavirus medic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
24d2e9ed-f49a-5c0c-bcd9-2019bd96fea6
DOI
10.12688/f1000research.50850.3
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identifying potential drug targets and candidate drugs for COVID-19: biological networks and structural modeling approachesDOI 10.12688/f1000research.50850.3
Transcriptome and SARS-CoV-2 biological network directed analysis for better therapeutic developmentSemantic proximity
A Connectivity Map-Based Drug Repurposing Study and Integrative Analysis of Transcriptomic Profiling of SARS-CoV-2 InfectionSemantic proximity
Repurposing novel therapeutic candidate drugs for coronavirus disease-19 based on protein-protein interaction network analysisSemantic proximity
In-silico discovery of common molecular signatures for which SARS-CoV-2 infections and lung diseases stimulate each other, and drug repurposingSemantic proximity
Network-Based Identification and Experimental Validation of Drug Candidates Toward SARS-CoV-2 via Targeting Virus–Host InteractomeSemantic proximity
COVID-19: A Drug Repurposing and Biomarker Identification by Using Comprehensive Gene-Disease Associations through Protein-Protein Interaction Network AnalysisSemantic proximity
Between viral targets and differentially expressed genes in COVID-19: the sweet spot for therapeutic intervention.Semantic proximity
Modeling COVID-19 disease biology to identify drug treatment candidatesSemantic proximity
A versatile and interoperable computational framework for the analysis and modeling of COVID-19 disease mechanismsSemantic proximity
Designing a Network Proximity-Based Drug Repurposing Strategy for COVID-19Semantic proximity
Identification of Drugs Targeting Multiple Viral and Human Proteins Using Computational Analysis for Repurposing Against COVID-19Semantic proximity
A comprehensive SARS-CoV-2-human protein-protein interactome network identifies pathobiology and host-targeting therapies for COVID-19Semantic proximity
Select a neighboring publication to make it the new centre.