Article

Marked Reduction in Viral Load and Symptoms in Breakthrough COVID-19 Cases Following AS03-Adjuvanted Plant-Made VLP Vaccination

2023-07-12

Abstract excerpt

Background: When SARS-CoV-2 breakthrough cases occur post-vaccination, only modest reductions in nasal viral load (VL) have been reported (ie: none to 10-fold). In a Phase 3 trial of an AS03-adjuvanted, plant-made, virus-like particle vaccine (CoVLP), 50- to 100-fold reductions in VL were observed at diagnosis in breakthrough cases caused by multiple variants. Herein, we report VL and symptom evolution in breakthr...

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Literature Corpus work: 23e573e4-aeb9-5d6a-ba86-7a813d6d3527
DOI: 10.2139/ssrn.4505340

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