Article
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccine-Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 9 Mar 2022
Pollett Simon D, Richard Stephanie A, Fries Anthony C, Simons Mark P, Mende Katrin, Lalani Tahaniyat, Lee Tida, Chi Sharon, Mody Rupal, Madar Cristian, Ganesan Anuradha, Larson Derek T, Colombo Christopher J, Colombo Rhonda, Samuels Emily C, Broder Christopher C, Laing Eric D, Smith Darci R, Tribble David, Agan Brian K, Burgess Timothy H
Abstract excerpt
Little is known about severe acute respiratory syndrome coronavirus 2 "vaccine-breakthrough" infections (VBIs). Here we characterize 24 VBIs in predominantly young healthy persons. While none required hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13 × 103 plaque-forming units/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC strains.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.