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Increased evolutionary rate in the 2014 West African Ebola outbreak is due to transient polymorphism and not positive selection

2014-11-14

Abstract excerpt

Gire et al. ( Science 345:1369–1372, 2014) analyzed 81 complete genomes sampled from the 2014 Zaire ebolavirus (EBOV) outbreak and reported “rapid accumulation of […] genetic variation” and a substitution rate that was “roughly twice as high within the 2014 outbreak as between outbreaks.” These findings have received widespread attention, and many have perceived Gire et al. (2014)’s results as implying rapid adap...

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Literature Corpus work
23d47196-dfa1-5a6f-a095-f8b0b529fb09
DOI
10.1101/011429
Open publication

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Increased evolutionary rate in the 2014 West African Ebola outbreak is due to transient polymorphism and not positive selectionDOI 10.1101/011429
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