Article
Virology. Mutation rate and genotype variation of Ebola virus from Mali case sequences.
Science (New York, N.Y.) - 3 Apr 2015
Hoenen T, Safronetz D, Groseth A, Wollenberg K R, Koita O A, Diarra B, Fall I S, Haidara F C, Diallo F, Sanogo M, Sarro Y S, Kone A, Togo A C G, Traore A, Kodio M, Dosseh A, Rosenke K, de Wit E, Feldmann F, Ebihara H, Munster V J, Zoon K C, Feldmann H, Sow S
Abstract excerpt
The occurrence of Ebola virus (EBOV) in West Africa during 2013-2015 is unprecedented. Early reports suggested that in this outbreak EBOV is mutating twice as fast as previously observed, which indicates the potential for changes in transmissibility and virulence and could render current molecular diagnostics and countermeasures ineffective. We have determined additional full-length sequences from two clusters of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.