Article

A translational MRI approach to validate acute axonal damage detection

2022-04-29

Abstract excerpt

Axonal degeneration is a central pathological feature of neurodegenerative pathologies and is closely associated with irreversible clinical disability. Current noninvasive methods to detect axonal damage in vivo are limited in their specificity, clinical applicability, and lack of proper validation. We aimed to validate an MRI framework based on multicompartment modeling of the diffusion-weighted signal (AxCalibe...

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Literature Corpus work: 23911928-f5ad-5e62-874d-c0f2f7c93324
DOI: 10.1101/2022.04.27.489694

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