Article

TRIM28 is a target for paramyxovirus V proteins

2025-05-19

Abstract excerpt

SUMO-modified Tripartite Motif Protein 28 (TRIM28; KAP1) plays a crucial role in repressing endogenous retroelement (ERE) transcription. We previously provided evidence that loss of SUMO-modified TRIM28 triggered by influenza A virus (IAV) infection promotes activation of host antiviral immunity via a mechanism involving derepression of EREs and production of immunostimulatory RNAs. While the IAV NS1 protein might...

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Literature Corpus work: 23288bea-58a8-572a-95e8-306bc58c9db7
DOI: 10.1101/2025.05.19.654852

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