Article

Spontaneous Reversal of Kallmann Syndrome in a Patient with PCSK1 and HS6ST1 Mutations: A Case Report

2025-07-09

Abstract excerpt

Kallmann syndrome (KS) is a form of hypogonadotropic hypogonadism (HH) characterized by gonadotropin-releasing hormone (GnRH) deficiency and anosmia due to defective neuronal migration. While traditionally considered irreversible, cases of spontaneous KS reversal have been reported, suggesting residual GnRH neuronal function in some individuals. We present a case of a 29-year-old man with KS who exhibited spontane...

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Literature Corpus work: 222b4340-0c81-576c-8ff0-dbf3c7de42a4
DOI: 10.20944/preprints202507.0792.v1

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