Article

Theileria annulata Hijacks Host Signaling: Integrated Phosphoproteomics and transcriptomics Unveils ERK1/2 as a Central Regulator of Host Transcription Factors

2024-08-27

Abstract excerpt

<title>Abstract</title> This study elucidates <italic>Theileria annulata’s</italic> manipulation of host cell signaling using phosphoproteomic and transcriptomic approaches. We unveil the parasite's control over multiple cellular processes, including apoptosis, calcium/calmodulin-dependent protein kinase (CAMK) regulation, and telomere maintenance. A central finding of our study is the parasite's targeted mani...

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Literature Corpus work: 20d7bf72-6ec8-5ad6-886c-7abd5b80026e
DOI: 10.21203/rs.3.rs-4975647/v1

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