Article

LncRNAH19 acts as a ceRNA of let-7g to facilitate EndMT in hypoxic pulmonary hypertension via regulating TGF-β signalling pathway

2024-05-14

Abstract excerpt

<title>Abstract</title> <p>Background Hypoxic pulmonary hypertension (HPH) is a challenging lung arterial disorder with remarkably high incidence and mortality rates, and the efficiency of current HPH treatment strategies is unsatisfactory. Endothelial-to-mesenchymal transition (EndMT) in the pulmonary artery plays a crucial role in HPH. Previous studies have shown that lncRNA-H19 (H19) is involved in many cardi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 20845640-056f-5e11-9503-248279bea3f0
DOI: 10.21203/rs.3.rs-4367962/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

LncRNAH19 acts as a ceRNA of let-7g to facilitate EndMT in hypoxic pulmonary hypertension via regulating TGF-β signalling pathwayDOI 10.21203/rs.3.rs-4367962/v1Read

Tibetan umbilical cord mesenchymal stem cell exosomes improve hypoxic pulmonary hypertension by inhibiting pulmonary vascular remodelingSemantic proximity Read

Long non-coding RNA H19 deficiency ameliorates bleomycin-induced pulmonary inflammation and fibrosisSemantic proximity Read

Knockdown of Long Noncoding RNA H19 Represses the Progress of Pulmonary Fibrosis through the Transforming Growth Factor β /Smad3 Pathway by Regulating MicroRNA 140Semantic proximity Read

Downregulation of long non-coding RNA H19 promotes P19CL6 cells proliferation and inhibits apoptosis during late-stage cardiac differentiation via miR-19b-modulated Sox6Semantic proximity Read

Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophySemantic proximity Read

Long non coding RNA H19: An emerging therapeutic target in fibrosing diseases.Semantic proximity Read

LncRNA H19 accelerates renal fibrosis by negatively regulating the let-7b-5p/TGF-βR1/COL1A1 axisSemantic proximity Read

Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarctionSemantic proximity Read

Overexpressed lncRNA AC068039.4 contributes to proliferation and cell cycle progression of pulmonary artery smooth muscle cells via sponging miR-26a-5p/TRPC6 in hypoxic pulmonary arterial hypertensionSemantic proximity Read

The overexpression of lncRNA H19 as a diagnostic marker for coronary artery diseaseSemantic proximity Read

LncRNA H19: A Novel Biomarker in Cardiovascular Disease.Semantic proximity Read

Long non-coding RNA-H19 antagonism protects against renal fibrosisSemantic proximity Read