The Chandrasekar Formulation (CSF-11): Evolution from an AI-Optimized Biomechanical Hypothesis to a TCGA-Grounded Intravenous Biophysical Protocol for Multi-Target Lung Adenocarcinoma Oncology

Abstract excerpt

<title>Abstract</title> <p>This paper presents the complete evolutionary arc of the Chandrasekar Formulation (CSF-11), an open-source computational oncology protocol engineered from mechanical engineering first principles. The foundational v1.0 framework employed an AI-Optimized Genetic Algorithm to derive a phytochemical composition Allicin (67.568%), Rosmarinic Acid (22.258%), Curcumin (3.180%), Quercetin (2.78...

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• CAR-T cell therapy research
• ErbB Receptors
• Molecular Docking Simulation
• Molecular Dynamics Simulation
• Mutation
• Phytochemicals
• Protein Binding
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

20644d91-66ad-5500-9412-bc64379a053b

DOI

10.21203/rs.3.rs-10042180/v1