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Identification of significant modules and hub genes involved in hepatic encephalopathy using WGCNA

24 Nov 2022

Abstract excerpt

BACKGROUND: Hepatic encephalopathy (HE) is a reversible syndrome of brain dysfunction caused by advanced liver disease. Weighted gene co-expression network analysis (WGCNA) could establish a robust co-expression network to identify the hub genes and underlying biological functions. This study was aimed to explore the potential therapeutic targets in HE by WGCNA. RESULTS: The green and brown modules were found to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36424620
DOI: 10.1186/s40001-022-00898-3

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