Article

Combined reference-free and multi-reference approaches uncover cryptic variation underlying rapid adaptation in microbial pathogens

2022-05-16

Abstract excerpt

<h4>Background</h4> Microbial species often harbor substantial functional diversity driven by structural genetic variation. Rapid adaptation from such standing variation in pathogens threatens global food security and human health. Genome wide association studies (GWAS) provide a powerful approach to identify genetic variants underlying recent pathogen evolution. However, the reliance on single reference genomes...

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Literature Corpus work: 1fcde859-0d66-5a8e-a1fb-9f35b53b2ac4
DOI: 10.1101/2022.05.16.492091

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