Article

Merfin: improved variant filtering and polishing via k-mer validation

2021-07-18

Abstract excerpt

Read mapping and variant calling approaches have been widely used for accurate genotyping and improving consensus quality assembled from noisy long reads. Variant calling accuracy relies heavily on the read quality, the precision of the read mapping algorithm and variant caller, and the criteria adopted to filter the calls. However, it is impossible to define a single set of optimal parameters, as they vary depend...

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Literature Corpus work: 1f56097f-b189-51ca-a6de-038d9f09196a
DOI: 10.1101/2021.07.16.452324

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