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Conserved core RNAi machinery in trematode-vectoring snails indicates gene silencing potential in the absence of classical systemic and amplification effectors

2026-07-14

Abstract excerpt

RNA interference (RNAi) is a widely exploited reverse-genetics tool with potential uses for disease control. Successful RNAi has been reported in trematode-vectoring snails, but the composition of RNAi effector-encoding gene complements, a key driver for RNAi efficiency, remain unstudied in these species. Using bioinformatics and comparative genomics, we searched for orthologues of 115 RNAi effector sequences in g...

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Literature Corpus work
1ef9bd86-b6b8-531c-abd0-421eb1b2a51a
DOI
10.64898/2026.07.10.737666
Open publication

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Conserved core RNAi machinery in trematode-vectoring snails indicates gene silencing potential in the absence of classical systemic and amplification effectorsDOI 10.64898/2026.07.10.737666
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