Article
New Insights Into Biomphalysin Gene Family Diversification in the Vector Snail Biomphalaria glabrata.
Frontiers in immunology - 1 Jan 2021
Pinaud Silvain, Tetreau Guillaume, Poteaux Pierre, Galinier Richard, Chaparro Cristian, Lassalle Damien, Portet Anaïs, Simphor Elodie, Gourbal Benjamin, Duval David
Abstract excerpt
Aerolysins initially characterized as virulence factors in bacteria are increasingly found in massive genome and transcriptome sequencing data from metazoans. Horizontal gene transfer has been demonstrated as the main way of aerolysin-related toxins acquisition in metazoans. However, only few studies have focused on their potential biological functions in such organisms. Herein, we present an extensive...
Topics
- Animals
- Biomphalaria
- Disease Vectors
- Evolution, Molecular
- Gene Duplication
- Genetic Variation
- Host-Parasite Interactions
- Multigene Family
- Phylogeny
- Pore Forming Cytotoxic Proteins