Article

Virtual screening of zinc compounds similar to NSAIDS with better pharmacodynamic and pharmacokinetic profiles

2023-04-26

Abstract excerpt

BACKGROUND : Pain is a common symptom that is managed in both outpatients and inpatients. There are many side effects associated with opioids such as respiratory depression, constipation, hyperalgesia, and tolerance. Non- steroidal anti-inflammatory drugs cause gastrointestinal tract (GIT) irritation and may be a risk factor for developing peptic ulcer disease. This study aimed to generate active analgesic agents...

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Literature Corpus work: 1eb8f858-d6e1-5767-b6ef-4ea916303412
DOI: 10.12688/f1000research.132017.1

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