Article

Sustained Delivery of MMP-9 siRNA via Thermosensitive Hydrogel Accelerates Diabetic Wound Healing

2021-02-22

Abstract excerpt

<title>Abstract</title> <p>Excessive expression of matrix metalloproteinase 9 (MMP-9) impedes healing of diabetic chronic wounds, thus wound dressing that could effectively inhibit the expression of MMP-9 offers significant clinical translation for diabetic wound healing. Herein, a hybrid hydrogel dressing was developed for localized and sustained delivery of MMP-9 siRNA (siMMP-9). siMMP-9 was complexed with Gly-...

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Literature Corpus work: 1dc2147f-df4a-54f5-b669-c6e755cfd2ab
DOI: 10.21203/rs.3.rs-208808/v1

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