Article

Cell Types of Origin in the Cell Free Transcriptome in Human Health and Disease

2021-05-05

Abstract excerpt

Cell-free RNA (cfRNA) can be used to noninvasively measure dynamic and longitudinal physiological changes throughout the body. While there is considerable effort in the liquid biopsy field to determine disease tissue-of-origin, pathophysiology occurs at the cellular level. Here, we describe two approaches to identify cell type contributions to cfRNA. First we used Tabula Sapiens , a transcriptomic cell atlas of t...

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Literature Corpus work: 1d4e248d-2df7-5a4f-8c40-7435d6df0890
DOI: 10.1101/2021.05.05.441859

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