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Novel potential inhibitor discovery against tyrosyl-tRNA synthetase fromStaphylococcus aureusby virtual screening, molecular dynamics, MMPBSA and QMMM simulations

2020-03-31

Abstract excerpt

The abuse and overuse of antibiotics is the main responsible for the raising antibiotic resistance among bacteria and as a consequence the of diseases severity and treatment complications. Staphylococcus aureus (S. aureus) can cause severe bloodstream infection, endocarditis and skin infection with an annual incidence of twenty-six cases per one hundred thousand people and approximately 30% of them are lethal. Amo...

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Literature Corpus work
1d315d1f-576c-53cd-a4e5-09b0df82197f
DOI
10.1080/08927022.2020.1726911
Open publication

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Novel potential inhibitor discovery against tyrosyl-tRNA synthetase fromStaphylococcus aureusby virtual screening, molecular dynamics, MMPBSA and QMMM simulationsDOI 10.1080/08927022.2020.1726911
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