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Article

Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics

14 Mar 2022

Abstract excerpt

Exosomes are secreted nanovesicles consisting of biochemical molecules, including proteins, RNAs, lipids, and metabolites that play a prominent role in tumor progression. In this study, we performed a label-free proteomic analysis of exosomes from a pair of homologous human colorectal cancer cell line with different metastatic abilities. A total of 115 exoDEPs were identified, with 31 proteins upregulated and 84...

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PMID: 35303583
DOI: 10.1016/j.tranon.2022.101389

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