Article

GPSNorm: Gaussian Process Spatial Normalization for Spatial Transcriptomics

2026-07-27

Abstract excerpt

Spatial transcriptomics technologies enable measurement of gene expression while preserving spatial tissue organization, but they remain highly sensitive to technical variability such as library size differences, slide-level effects, and spatial artifacts. Most existing normalization approaches treat normalization as a preprocessing step and perform downstream analyses on normalized values as fixed inputs, ignorin...

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Literature Corpus work: 1c28ac8d-7fec-56ec-8f82-556436f597d8
DOI: 10.64898/2026.07.23.740319

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