Cartilage proteomics: Challenges, solutions and recent advances.

Abstract excerpt

The mammalian skeleton is largely composed of cartilage and bone. The major functions of cartilage are first to provide a transient template for development of the axial and appendicular skeleton and secondly to provide permanent articulating joint surfaces. The unique cartilage extracellular matrix (ECM) is essential for the load-bearing and viscoelastic properties of cartilage tissues. Maintained by the chondroc...

Topics

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• Advanced Proteomics Techniques and Applications
• Cartilage, Articular
• Cell Adhesion Molecules Research
• Disease Progression
• Extracellular Matrix
• Glycosylation and Glycoproteins Research
• Mutation
• Osteoarthritis Treatment and Mechanisms

Identifiers and source

Literature Corpus work

1be48b63-de32-5b23-b6a0-19514b3e367c

DOI

10.1002/prca.200780007