Article
SeRenDIP-CE: Sequence-based Interface Prediction for Conformational Epitopes
2020-11-20
Abstract excerpt
<h4>Motivation</h4> Antibodies play an important role in clinical research and biotechnology, with their specificity determined by the interaction with the antigen’s epitope region, as a special type of protein-protein interaction (PPI) interface. The ubiquitous availability of sequence data, allows us to predicting epitopes from sequence in order to focus time-consuming wet-lab experiments onto the most promisin...
Topics
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- Advanced Biosensing Techniques and Applications
- Glycosylation and Glycoproteins Research
- Immunotherapy and Immune Responses
- Machine Learning in Bioinformatics
- Monoclonal and Polyclonal Antibodies Research
- Protein purification and stability
- RNA and protein synthesis mechanisms
- vaccines and immunoinformatics approaches
Identifiers and source
- Literature Corpus work
- 1bdbf1cb-d208-51da-b8a8-3e3016777e3c
- DOI
- 10.1101/2020.11.19.390500