Article
Transcriptome Analysis of the Mouse Medial Prefrontal Cortex in Chronic Constriction Injury Model: Implications of neuropathic pain-induced cognitive impairment
2022-09-30
Abstract excerpt
Chronic pain patients often complain their decreased cognitive function. However, the comorbidity mechanism between neuropathic pain and cognitive dysfunction still remains largely unknown. Here, we examined changes in the transciptomic profiles in the medial prefrontal cortex (mPFC) of mice with chronic pain and cognitive impairment using RNA sequencing (RNA-seq) technology. A mouse model of peripheral neuropathi...
Topics
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- Fibromyalgia and Chronic Fatigue Syndrome Research
- Hereditary Neurological Disorders
- Musculoskeletal pain and rehabilitation
- Nerve injury and regeneration
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuropeptides and Animal Physiology
- Pain Mechanisms and Treatments
- Pharmacological Effects of Natural Compounds
Identifiers and source
- Literature Corpus work
- 1bc34bd0-c16d-5891-970f-baf2d8e844dc
- DOI
- 10.21203/rs.3.rs-2108118/v1
