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Article

Intestinal organoids for Cystic Fibrosis research

28 Nov 2019

Abstract excerpt

Significant progress has been made in the development of CFTR modulator therapy; however, current CFTR modulator therapies are only available for a minority of the CF-patient population. Additionally, heterogeneity in in vivo modulator response has been reported among individuals carrying homozygous F508del-CFTR, adding to the desire for an optimal prediction of response-to-therapy on an individual level. In the...

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PMID: 31787574
DOI: 10.1016/j.jcf.2019.11.002

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