Article

Using Culture-Enriched Phenotypic Metagenomics for Targeted High-Throughput Monitoring of Clinically-Important Fraction of Beta-Lactam Resistome

2022-04-06

Abstract excerpt

The high bacterial community complexity greatly hinders the monitoring of clinically prevalent extended-spectrum beta-lactam resistant bacteria, which are usually present as rare but key populations involving in the environmental dissemination of clinical resistance. Here, we introduce culture-enriched phenotypic metagenomics that integrates culture enrichment, phenotypic screening and metagenomic analyses as an e...

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Literature Corpus work: 1a8240c6-f56e-5ff4-a930-b3ee8882cd58
DOI: 10.1101/2022.04.06.487307

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