Article

Vertical transmission of maternal DNA through extracellular vesicles associates with altered embryo bioenergetics during the periconception period

2023-04-21

Abstract excerpt

<h4>Summary</h4> The transmission of DNA through extracellular vesicles (EVs) represents a novel genetic material transfer mechanism that may impact genome evolution and tumorigenesis. We aimed to investigate the potential for vertical DNA transmission within maternal endometrial EVs to the pre-implantation embryo and describe any effect on embryo bioenergetics. We discovered that the human endometrium secretes a...

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Literature Corpus work: 19f0e6ae-99a3-57a7-975a-3b8d79ccfc64
DOI: 10.1101/2023.04.21.537765

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