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Vertical transmission of maternal DNA through extracellular vesicles associates with altered embryo bioenergetics during the periconception period

23 Jun 2023

Abstract excerpt

The transmission of DNA through extracellular vesicles (EVs) represents a novel genetic material transfer mechanism that may impact genome evolution and tumorigenesis. We aimed to investigate the potential for vertical DNA transmission within maternal endometrial EVs to the pre-implantation embryo and describe any effect on embryo bioenergetics. We discovered that the human endometrium secretes all three general...

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PMID: 38149847
DOI: 10.7554/elife.88008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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