Back to search

Article

Product characterization and preclinical evaluation of the biodistribution and safety of umbilical cord mesenchymal stromal cell-derived extracellular vesicles

2023-07-19

Abstract excerpt

<title>Abstract</title> <p>Background Extracellular vesicles (EVs) represent a new axis of intercellular communication that can be explored for therapeutic purposes; they have garnered considerable attention for their potential as cell-free therapy. The clinical application of mesenchymal stromal cell (MSC)-derived EVs is still in its infancy and faces many challenges. The heterogeneity inherent to MSCs, differe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
19c94db4-fae0-58de-bba5-dd601505e6ff
DOI
10.21203/rs.3.rs-2949774/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Product characterization and preclinical evaluation of the biodistribution and safety of umbilical cord mesenchymal stromal cell-derived extracellular vesiclesDOI 10.21203/rs.3.rs-2949774/v1
Safety Evaluation of Long-term Administration of Umbilical Mesenchymal Stem Cell-Derived Extracellular VesiclesSemantic proximity
Toxicological profile of Umbilical Cord Blood-derived small Extracellular VesiclesSemantic proximity
Small extracellular vesicles (sEVs): discovery, functions, applications, detection methods and various engineered formsSemantic proximity
Extracellular Vesicle-Enriched Secretome from Mesenchymal Stromal Cells Protects Against Chemically, Particulate-, and Ischemia-Induced Innate-Immunity Induced InflammationSemantic proximity
MSC-EVs and UCB-EVs promote skin wound healing and spatial transcriptome analysisSemantic proximity
Liver-Targeted Fetal MSC-Derived Extracellular Vesicles: A Therapeutic Approach in a Mouse Model of Acute Hepatic FailureSemantic proximity
Engineered Extracellular Vesicles from Adipose-Derived Stem Cells: Translational Strategies from Genetic Engineering to Scalable ProductionSemantic proximity
Potential Druggability of Mesenchymal Stem/Stromal Cell-derived ExosomesSemantic proximity
Immunomodulatory properties of umbilical cord blood-derived small extracellular vesicles and their therapeutic potential for inflammatory skin disordersSemantic proximity
Extracellular Vesicles Derived From Adult and Fetal Bone Marrow Mesenchymal Stromal Cells Differentially Promote ex vivo Expansion of Hematopoietic Stem and Progenitor CellsSemantic proximity
Clinical Translation of Extracellular VesiclesSemantic proximity
Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle productionSemantic proximity
Select a neighboring publication to make it the new centre.