Article

Architecture of the chikungunya virus replication organelle

2022-04-06

Abstract excerpt

Alphaviruses are mosquito-borne viruses that cause serious disease in humans and other mammals. Along with its mosquito vector, the alphavirus chikungunya virus (CHIKV) has spread explosively in the last 20 years, and there is no approved treatment for chikungunya fever. On the plasma membrane of the infected cell, CHIKV generates dedicated organelles for viral RNA replication, so-called spherules. Whereas structu...

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Literature Corpus work: 194f0e95-f391-575d-ac3f-f6b6d7617c81
DOI: 10.1101/2022.04.05.487153

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