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Changes in the Genital Microbiome and Inflammation Among Women Using 30-Day <i>L. Rhamnosus/L. Reuteri</i> Probiotic in Combination with Intravaginal Estradiol: Findings from a Pilot, Open-Label, Phase I Clinical Trial

2025-12-04

Abstract excerpt

A dysbiotic genital microbiome can cause inflammation, higher sexually transmitted infection risk, and long-term effects even when asymptomatic. Probiotic Lactobacillus species can potentially improve the genital microbial environment, especially among women with bacterial vaginosis (BV). Further, the hormone estradiol has been linked to mucosal health and better Lactobacillus colonization. We evaluated the impa...

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Literature Corpus work
1886b8cd-653b-5bfa-b149-f1e7a85644e2
DOI
10.64898/2025.12.03.25341486
Open publication

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Changes in the Genital Microbiome and Inflammation Among Women Using 30-Day <i>L. Rhamnosus/L. Reuteri</i> Probiotic in Combination with Intravaginal Estradiol: Findings from a Pilot, Open-Label, Phase I Clinical TrialDOI 10.64898/2025.12.03.25341486
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