When Mast Cells Run Amok: A Comprehensive Review and Case Study on Severe Neonatal Diffuse Cutaneous Mastocytosis

Abstract excerpt

Neonatal diffuse cutaneous mastocytosis (NDCM) is defined as the infiltration of the epidermis by a clonal proliferation of mast cells, observed at birth, without initial signs of systemic involvement. The typical driver mutation is located in the KIT gene. We report a rare case of a boy, born at term, presenting already at birth with generalized subcutaneous nodules, on the face, scalp, trunk, back, hands, and fe...

Topics

Open a Topic to create a Post that cites this publication.

• Age Factors
• Cell Degranulation
• Consensus
• Mast Cells
• Practice Guidelines as Topic
• Protein Kinase Inhibitors
• Severity of Illness Index
• Skin

Identifiers and source

Literature Corpus work

1886b1a8-3b93-5dfc-87a6-b9c3b2b8e6bf

DOI

10.20944/preprints202310.0023.v1