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Intestinal flow rates, absorption of felodipine from the small intestine and attributes of chyme collected at midgut from Labradors

2024-01-08

Abstract excerpt

The objectives of the present study were (1) to investigate gastrointestinal hydrodynamics of Labradors as a model for human midgut (2) to examine various attributes of intestinal fluids in vivo and (3) to study the influence of hydrodynamics on the dissolution and absorption of a poorly soluble drug from various suspensions. Gastrointestinal flow rates were determined volumetrically using an aspiration method. Is...

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Literature Corpus work
186f83b4-4520-523f-975e-51fb8ccb4846
DOI
10.1101/2024.01.05.574377
Open publication

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