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Comprehensive analysis of Six2-mediated transcriptional regulatory network in ccRCC

2022-03-10

Abstract excerpt

<h4>Background: </h4> Six2, a transcription factor, exerts an oncogenic role in clear cell renal cell carcinoma (ccRCC). Increased Six2 expression could enhance cancer metastasis. However, the regulatory action of Six2 remains unclear in cancer. The purpose of this study is to analyze the regulatory pattern and potential downstream effectors of Six2.MethodsFirstly, transcriptional data in TCGA-KIRC cohorts was use...

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Literature Corpus work
1859300c-d06a-554f-a627-21dda7969ad0
DOI
10.21203/rs.3.rs-1394889/v1
Open publication

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