Article

Telomere-to-Telomere Assembly Improves Host Reads Removal in Metagenomic High-Throughput Sequencing of Human Samples

2023-05-07

Abstract excerpt

<h4>ABSTRACT</h4> Metagenomic high-throughput sequencing brings revolution to the study of human microbiome, clinical pathogen detection, discovery and infection diagnosis, but clinical samples often contain abundant human nucleic acids, leading to a high proportion of host reads. A high-quality human reference genome is essential for removing host reads to make downstream analyses faster and more accurate. The r...

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Literature Corpus work: 18076054-2246-5f44-a812-3af89cb1027e
DOI: 10.1101/2023.05.05.539517

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