Article
Value and significance of brain radiation therapy during first-line EGFR-TKI treatment in lung adenocarcinoma with EGFR sensitive mutation and synchronous brain metastasis: Appropriate timing and technique.
Thoracic cancer - 1 Dec 2021
Gu Yangchun, Xu Yan, Zhuang Hongqing, Jiang Weijuan, Zhang Hua, Li Xiaofeng, Liu Yonggang, Ma Li, Zhao Dahai, Cheng Yuan, Yu Yan, Liu Ping, Qin Jianwen, Chen Xueqin, Gao Junzhen, Wang Mengzhao, Liang Li, Cao Baoshan
Abstract excerpt
BACKGROUND: For lung adenocarcinoma patients with epidermal growth factor receptor (EGFR) sensitive mutation and synchronous brain metastasis (syn-BM), when and how to apply radiotherapy (RT) during first-line tyrosine kinase inhibitor (TKI) treatment remains debatable. METHODS: From a real-world multicenter database, EGFR-mutant patients with syn-BM diagnosed between 2010-2020 and treated with first-line TKIs...
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