Article

Interleukin-17-based cytokine signaling as a determinant for tumor immune microenvironment with prognostic value in triple-negative breast cancer

2021-06-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Only a proportion of triple-negative breast cancer (TNBC) is immunotherapy-responsive. We hypothesized that the tumor microenvironment (TME) might influence the outcomes of TNBC and investigated the relevant signaling pathways. <bold>Methods:</bold> RNA-seq data of 115 TNBC samples and 112 normal adjacent tissues were retrieved for ESTIMATE, CIBERSORTx, X2K, KEG...

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Literature Corpus work: 17b3a9c0-1d86-5874-a5aa-51d7468df8b4
DOI: 10.21203/rs.3.rs-495771/v1

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